Generally speaking, you’re correct–the large scale decoders are essentially the same as their small-scale counterparts, except with higher current (and sometimes higher voltage) capacities. There may be subtle differences with regard to the number of lighting function outputs or smoke unit drivers or stuff like that depending on the particular decoders in question, but by and large they’re at least very similar. I’d stick with decoders that are rated for at least 3 amps for most large scale locos. You can get away with the 1-amp HO decoders for really small “critter” type locomotives or small 0-4-0 or similar locos that don’t draw much current.
In terms of which decoders, there are lots of options and twice as many opinions. Many folks opt for decoders which combine motor control and sound in one decoder. QSI’s “Titan” decoder is highly regarded, and is one that I use myself. I’ve played with the ESU/Loksound v4.0 at a train show, and liked what I saw and heard, but I’ve not had the opportunity to install one yet myself. (I run battery power, so it’s only just recently that the ability to use generic DCC decoders in that environment has become practical.) Other motor/sound decoders which seem to be popular with large scale come from Zimo and Massoth. Soundtraxx (Tsunami) and TCS are big players in small scale decoders, but to date do not have large scaled decoders available. But definitely keep them in mind for the smaller locos. I’ve got Tsunami decoders in my two “Galloping Goose” railcars. I don’t pay much attention to the motor-only decoders.
As Dave suggests, head down to the “Power and Sound” forum with questions about specific decoders you may be thinking about using, and also mention which locos you’re thinking of installing them in. There may be subtle nuances which might favor one decoder over another for a given installation.
And welcome to LSC!
Later,
K